A Case of Cogan's Syndrome With Angina

Jong Sang Kim1, Ja Be Park, Jung Chul Joo

  • 1Division of Cardiology, Department of Internal Medicine, Sahmyook Medical Center, Seoul Adventist Hospital, Seoul, Korea.

Insights

Cogan

Area of Science:

  • Rheumatology
  • Cardiology
  • Ophthalmology

Background:

  • Cogan's syndrome is a rare systemic inflammatory disease.
  • Diagnosis relies on characteristic inner ear and ocular inflammation, alongside large vessel vasculitis.
  • Aortitis can manifest as a complication, potentially affecting coronary arteries.

Purpose of the Study:

  • To present a case of Cogan's syndrome presenting with cardiac symptoms.
  • To highlight the link between aortitis in Cogan's syndrome and coronary ostial stenosis.
  • To emphasize the importance of considering cardiac involvement in Cogan's syndrome.

Main Methods:

  • Case report detailing clinical presentation, diagnostic workup, and management.
  • Review of relevant literature on Cogan's syndrome and its cardiovascular manifestations.

Main Results:

  • The patient presented with stable angina.
  • Coronary ostial stenosis was identified as the cause of angina.
  • Aortitis secondary to Cogan's syndrome was confirmed as the underlying pathology.

Conclusions:

  • Cogan's syndrome can lead to significant cardiovascular complications, including coronary ostial stenosis due to aortitis.
  • Early recognition and management of cardiac involvement are crucial for patients with Cogan's syndrome.
  • This case underscores the systemic nature of Cogan's syndrome and its potential impact on major arteries.

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