Related Experiment Video
Updated: Jun 4, 2026

Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Chromosome 1p abnormalities in B non Hodgkin's lymphoma
E van den Berghe1, C de Wolf-Peeters, A Louwagie
1Centre for Human Genetics, AZ St. Jan, Brugge, Belguim.
Abstract:
Thirteen patients with B-non Hodgkin's lymphoma and abnormalities of the short arm of chromosome 1 were evaluated, to see if this cytogenetic anomaly was associated with a particular subgroup of lymphomas. Large cell lymphoma was found in seven patients (with an immunoblastic component in four cases). Six patients with diffuse small cleaved cell lymphoma of non follicle centre cell origin formed a second group. The chromosome 1 breakpoints in the second group were located between p34 and p36, suggesting that genes located here may be important in the initiation or progression of these lymphomas.
Related Concept Videos
Abnormal Proliferation
Karyotyping
Non-LTR Retrotransposons
Polytene Chromosomes
Nondisjunction
Lampbrush Chromosomes
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops resemble the...

