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Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Liver abscess caused by periodontal bacterial infection with Fusobacterium necrophorum
Masato Yoneda1, Shingo Kato, Hironori Mawatari
1Division of Gastroenterology Department of Oral and Maxillofacial Surgery, Yokohama City University Graduate School of Medicine, Yokohama Department of Pharmacology, Osaka University, Graduate School of Dentistry, Suita, Osaka, Japan.
Abstract:
Liver abscess is recognized as a life-threatening disease. However, even in recent years, approximately 50% of liver abscess cases are considered to be cryptogenic. Here, we report a case of liver abscess associated with periodontal bacterial infection by Fusobacterium necrophorum, which is commonly found in the oropharyngeal flora. A 36-year-old man presented with fever and contrast-enhanced abdominal computed tomography revealed multiple liver abscesses. F.necrophorum was isolated from oral smears, liver aspirates and blood samples. Liver abscesses caused by periodontal bacterial infection are rare, however, the incidence is expected to increase in the future, as periodontitis is extremely common and is on the rise as one of the most common chronic infections in the world. A systemic survey including periodontitis may be required for the exact diagnosis of the source of infection.
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