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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: Jun 4, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Glaucoma anterior chamber morphometry based on optical Scheimpflug images.

Ruiz Simonato Alonso1, Renato Ambrósio Junior, Augusto Paranhos Junior

  • 1Department of Ophthalmology, Universidade Federal Fluminense, Rio de Janeiro, RJ, Brazil. ruizsa@hotmail.com

Arquivos Brasileiros De Oftalmologia
|January 29, 2011
PubMed
Summary

The Pentacam HR effectively identifies eyes at risk for angle closure using anterior chamber angle (ACA), volume (ACV), and depth (ACD) measurements. This noncontact method shows high specificity in detecting narrow angles, aiding in glaucoma screening.

Related Experiment Videos

Last Updated: Jun 4, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Glaucoma Research

Background:

  • Accurate evaluation of the anterior chamber angle (ACA) is crucial for diagnosing and managing glaucoma.
  • Traditional gonioscopy is subjective and can be time-consuming.
  • Noncontact anterior segment imaging offers a potentially more objective and efficient alternative.

Purpose of the Study:

  • To compare the diagnostic performance of gonioscopy with noncontact anterior chamber tomography (High Resolution Pentacam - HR) using optical Scheimpflug images.
  • To evaluate the ability of the Pentacam HR in assessing anterior chamber angle (ACA) measurements.
  • To determine the efficacy of Pentacam HR in identifying eyes at risk for angle closure.

Main Methods:

  • A transversal study involving 112 eyes from 74 subjects was conducted.
  • Gonioscopy was performed and graded using the Shaffer Classification (SC).
  • Pentacam HR imaging was used to obtain automated measurements of ACA, anterior chamber volume (ACV), and anterior chamber depth (ACD).

Main Results:

  • Gonioscopy classified 60.07% of eyes as open-angle and 33.93% as narrow-angle.
  • Pentacam HR measurements showed significantly different ACA, ACV, and ACD between open-angle and narrow-angle groups (p<0.001 for ACV, p<0.0001 for ACD).
  • Receiver Operating Characteristic (ROC) curve analysis demonstrated 52.6% sensitivity and 100% specificity for Pentacam HR in screening eyes with ACA ≤ 20º (SC Grade 2).

Conclusions:

  • The Pentacam HR, utilizing optical Scheimpflug imaging, is capable of assessing anterior chamber dimensions.
  • The system demonstrated significant differences in ACV and ACD between open and narrow angles.
  • Pentacam HR shows promise in detecting eyes at risk for angle closure by analyzing ACV and ACD, with high specificity.