Not takotsubo: a different form of stress-induced cardiomyopathy--a case series

Cho M Win1, Amit Pathak, Maya Guglin

  • 1University of South Florida and Tampa General Hospital, Tampa, FL 33606, USA.

Insights

Stress-induced cardiomyopathy, often diagnosed by apical ballooning, can also manifest as transient global left ventricular dysfunction. This finding expands the spectrum of reversible cardiac conditions associated with severe illness.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Stress-induced cardiomyopathy (SIC) diagnosis typically relies on regional wall motion abnormalities, classically apical ballooning.
  • Takotsubo cardiomyopathy is a common form of SIC.

Observation:

  • Three cases of transient global left ventricular systolic dysfunction during severe medical illness are presented.
  • These cases mimicked takotsubo cardiomyopathy but lacked regional wall motion abnormalities.

Findings:

  • The observed cardiomyopathy showed reversibility, mild troponin elevation, non-specific ECG changes, and negative ischemia work-up.
  • Global left ventricular dysfunction, distinct from regional wall motion abnormalities, is a potential presentation of SIC.

Implications:

  • The spectrum of stress-induced cardiomyopathy may include global left ventricular dysfunction, not solely regional patterns.
  • Recognizing global dysfunction as a variant of SIC is crucial for accurate diagnosis and management in critically ill patients.

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