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Updated: Jun 4, 2026

Identification and Isolation of Burst-Forming Unit and Colony-Forming Unit Erythroid Progenitors from Mouse Tissue by Flow Cytometry
Published on: November 4, 2022
Erythropoietin surprises: an immune saga
1Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. hbroxmey@iupui.edu
Abstract:
Erythropoietin (EPO) an erythropoietic stimulating agent also exerts effects on other cell systems. Nairz et al. (2011) now link EPO and intracellular signaling through the EPO receptor (EPOR) to innate immune cell activity via macrophages.
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Thrombopoietin (TPO), mainly released by the liver,...
Factors Affecting Erythropoiesis
Several factors influence the erythrocyte production rate, with tissue oxygen level being among the most critical. Intense exercise or high altitudes can cause tissue hypoxia, which triggers the kidneys to release more erythropoietin (EPO) into the bloodstream.
EPO then...