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Related Concept Videos

Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

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Related Experiment Video

Updated: Jun 4, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
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Published on: May 22, 2019

Central poststroke pain: a population-based study.

Henriette Klit1, Nanna Brix Finnerup, Grethe Andersen

  • 1Danish Pain Research Center, Aarhus University Hospital, Norrebrogade 44, Building 1A, DK-8000 Aarhus C, Denmark Department of Neurology, Aarhus University Hospital, Norrebrogade 44, Building 10, DK-8000 Aarhus C, Denmark.

Pain
|January 29, 2011
PubMed
Summary
This summary is machine-generated.

Central poststroke pain (CPSP) affects over 7% of stroke survivors, significantly impacting their quality of life and rehabilitation. Early assessment of this condition is crucial for effective management.

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Last Updated: Jun 4, 2026

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Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain
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Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain

Published on: July 18, 2016

Area of Science:

  • Neurology
  • Pain Medicine
  • Epidemiology

Background:

  • Central poststroke pain (CPSP) is a direct consequence of cerebrovascular lesions.
  • Knowledge regarding CPSP epidemiology and clinical characteristics is limited.
  • CPSP is often neglected despite its significant impact on stroke survivors.

Purpose of the Study:

  • To determine the prevalence and clinical characteristics of CPSP in a defined population.
  • To highlight the importance of assessing pain in stroke survivors.

Main Methods:

  • Population-based study utilizing questionnaires sent to stroke patients (n=964) in Aarhus County, Denmark.
  • Clinical examinations were performed on patients meeting CPSP criteria (n=51).
  • Stringent criteria and standardized examinations were used for pain classification.

Main Results:

  • The minimum prevalence of definite or probable CPSP was 7.3%.
  • CPSP-like dysesthesia or pain prevalence was 8.6%.
  • Specific sensory alterations included pinprick hyperalgesia (57%), cold allodynia (40%), and brush-evoked dysesthesia (51%).

Conclusions:

  • CPSP is a significant condition with a notable prevalence post-stroke.
  • Pain negatively impacts quality of life and rehabilitation outcomes.
  • Routine assessment of pain in stroke survivors is recommended.