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Published on: September 19, 2019
Mild-to-moderate neurogenic pyrexia in acute cerebral infarction
Gang Li1, Xiao-yun Xu, Yue Wang
1Department of Neurology, East Hospital, Tongji University, Shanghai, PR China.
European Neurology
|January 29, 2011
Summary
Mild-to-moderate neurogenic pyrexia in acute cerebral infarction patients indicates a similar prognosis to infectious pyrexia. This type of fever may be linked to stroke severity, with earlier onset and shorter duration than infectious causes.
Area of Science:
- Neurology
- Internal Medicine
- Critical Care Medicine
Background:
- Fever (pyrexia) is linked to poor outcomes after stroke.
- Limited data exists on the impact of different causes of post-stroke fever, particularly mild-to-moderate neurogenic pyrexia, on stroke prognosis in acute cerebral infarction.
Purpose of the Study:
- To compare clinical features, pyrexia characteristics, and prognosis in acute cerebral infarction patients with mild-to-moderate neurogenic pyrexia, infectious pyrexia, and no pyrexia.
- To specifically investigate the prognosis of mild-to-moderate neurogenic pyrexia.
Main Methods:
- Prospective analysis of clinical data from 709 patients with acute cerebral infarction.
- Comparison of three groups: mild-to-moderate neurogenic pyrexia, infectious pyrexia, and no pyrexia.
Main Results:
- Patients with mild-to-moderate neurogenic pyrexia and infectious pyrexia had higher NIHSS scores and mortality rates, and lower Barthel Index scores at 3 months compared to those without pyrexia.
- No significant differences in age, gender, or comorbidities were found among the groups.
- Mild-to-moderate neurogenic pyrexia presented with earlier onset and shorter duration than infectious pyrexia.
Conclusions:
- Mild-to-moderate neurogenic pyrexia in acute cerebral infarction patients is associated with a prognosis similar to infectious pyrexia.
- Neurogenic pyrexia may be related to the severity of the stroke.
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