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Xanthine and hypoxanthine in amniotic fluid during pregnancy
N Kjaergaard1, J F Møller-Petersen, F V Kristiansen
1Department of Gynaecology and Obstetrics, Aalborg Hospital.
Danish Medical Bulletin
|December 1, 1990
Summary
This study establishes the first reference range for xanthine and hypoxanthine in amniotic fluid. Most pregnant women studied showed low concentrations, suggesting normal fetal oxygenation.
Area of Science:
- Biochemistry
- Perinatal Medicine
- Biomarkers
Background:
- Xanthine and hypoxanthine are established indicators of cellular hypoxia.
- Amniotic fluid analysis offers a non-invasive window into fetal well-being.
- Establishing normative values is crucial for interpreting biomarker concentrations.