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Published on: October 3, 2019
An atypical cutaneous reaction to rivastigmine transdermal patch
1Department of Dermatology, Universitá di Roma "La Sapienza", Viale del Policlinico, 155, 00161 Rome, Italy.
Journal of Allergy
|January 29, 2011
Summary
Rivastigmine patches improve cognition in dementia but can cause skin reactions. This report details a rare case of allergic sensitization to the rivastigmine patch in an Alzheimer's patient.
Area of Science:
- Neurology
- Dermatology
- Pharmacology
Background:
- Rivastigmine, a cholinesterase inhibitor, treats cognitive decline in Alzheimer's and Parkinson's dementia.
- Available orally or via transdermal patch, the patch offers superior patient compliance.
- Common side effects include irritative dermatitis.
Observation:
- A patient with Alzheimer's dementia developed a skin reaction to the rivastigmine patch.
- This reaction was identified as active sensitization.
Findings:
- This case represents the second documented instance of active sensitization to rivastigmine transdermal patches.
- The findings highlight a rare but significant adverse cutaneous reaction.
Implications:
- Clinicians should be aware of the potential for allergic sensitization to rivastigmine patches.
- Further investigation into managing and preventing such dermatological side effects is warranted.
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