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Updated: Jun 4, 2026

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
Published on: December 5, 2025
Airway management in critically ill patients
Donald E G Griesdale1, William R Henderson, Robert S Green
1Division of Critical Care Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada. dgriesdale@post.harvard.edu
Securing the airway via endotracheal intubation in critically ill patients carries significant risks. This review covers airway assessment, optimization, and techniques to minimize complications like hypoxemia and hypotension.
Area of Science:
- Critical Care Medicine
- Anesthesiology
- Emergency Medicine
Background:
- Endotracheal intubation in critically ill patients presents a high risk of severe complications.
- Hypoxemia and hypotension are significant risks associated with this procedure.
Purpose of the Study:
- To review definitions, complications, and airway assessment for endotracheal intubation in critically ill patients.
- To discuss patient optimization, airway management techniques, and risk mitigation strategies.
Main Methods:
- Literature review of existing studies and guidelines on endotracheal intubation in critically ill patients.
- Synthesis of information regarding airway assessment, patient optimization, and procedural techniques.
- Analysis of strategies to minimize difficult or failed intubations and associated complications.
Main Results:
- Critically ill patients face elevated risks of hypoxemia and hypotension during intubation.
- Comprehensive airway assessment and patient optimization are crucial for successful intubation.
- Various techniques and strategies exist to manage difficult airways and mitigate severe complications.
Conclusions:
- Effective airway management in critically ill patients requires thorough assessment, optimization, and skilled technique.
- Minimizing the risk of difficult or failed intubation is paramount to patient safety.
- Proactive strategies are essential to prevent life-threatening complications during endotracheal intubation.
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