Related Experiment Video
Updated: Jun 4, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Does anesthesiologist-directed sedation for ERCP improve deep cannulation and complication rates?
Paresh P Mehta1, John J Vargo, John A Dumot
1Department of Internal Medicine, Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.
Gastroenterologist-directed sedation (GDS) and anesthesiologist-directed sedation (ADS) for endoscopic retrograde cholangiopancreatography (ERCP) showed similar deep cannulation success rates. Complication rates were also comparable between the two sedation approaches in this study.
Area of Science:
- Gastroenterology
- Anesthesiology
- Medical Procedures
Background:
- Sedation for endoscopic retrograde cholangiopancreatography (ERCP) can be managed by gastroenterologists or anesthesiologists.
- Limited data exists comparing deep cannulation success and complication rates between these two sedation approaches.
- Anesthesiologist-directed sedation (ADS) theoretically may improve deep cannulation due to consistent sedation levels and dedicated monitoring.
Purpose of the Study:
- To compare the success rates of deep cannulation during ERCP.
- To evaluate procedural complication rates between gastroenterologist-directed sedation (GDS) and ADS.
- To determine if sedation provider impacts ERCP outcomes.
Main Methods:
- A retrospective review of ERCPs performed by senior endoscopists over two years.
- Sedation was managed by GDS (narcotic and benzodiazepine) in year one and ADS in year two.
- Patients with prior papillary interventions were excluded; deep cannulation success and complications were recorded.
Main Results:
- A total of 367 patients were analyzed: 178 (48.5%) under GDS and 189 (51.5%) under ADS.
- No significant differences were observed in demographics between the GDS and ADS groups.
- Overall cannulation success rates were similar (94.4% GDS vs. 95.2% ADS, P=0.36), with comparable complication profiles.
Conclusions:
- Deep ductal cannulation rates during ERCP are similar regardless of whether sedation is provided by gastroenterologists or anesthesiologists.
- The choice of sedation provider (GDS vs. ADS) does not appear to significantly impact ERCP deep cannulation success.
- Complication rates were also comparable between the GDS and ADS groups.
Related Concept Videos
Endoscopic Procedures V: ERCP
Patient...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Parenteral Anesthetics: Overview
Stages of General Anesthesia
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...