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Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

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Published on: December 15, 2014

Optimized density-weighted imaging for dynamic contrast-enhanced 3D-MR mammography.

Marcel Gutberlet¹, Anne Roth, Dietbert Hahn

¹Institut für Radiologie, Medizinische Hochschule Hannover, Hannover, Germany. Gutberlet.Marcel@mh-hannover.de

Journal of Magnetic Resonance Imaging : JMRI

|January 29, 2011

Summary

New 3D dynamic contrast-enhanced MR mammography techniques, virtual coils for effective DW (VIDED) and alternating DW (ADW) imaging, significantly improve spatial resolution and reduce slice crosstalk. These methods enhance field of view without increasing scan time or requiring multichannel coils.

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Area of Science:

Magnetic Resonance Imaging (MRI)
Medical Imaging
Radiology

Background:

3D dynamic contrast-enhanced (DCE) MR mammography aims to improve spatial coverage and reduce slice crosstalk.
Achieving optimal signal-to-noise ratio (SNR) is crucial for diagnostic accuracy.

Purpose of the Study:

To enhance spatial coverage and reduce slice crosstalk in 3D DCE MR mammography.
To maintain an optimal signal-to-noise ratio (SNR) during imaging.

Main Methods:

Asymmetric sampling schemes and virtual coil reconstruction for density-weighted (DW) 3D imaging (VIDED).
Alternating DW (ADW) sampling to shift undersampling artifacts.
Comparison of VIDED and ADW with conventional Cartesian imaging in phantom and in vivo studies.

Main Results:

VIDED significantly reduced slice crosstalk and increased SNR by 16% compared to Cartesian imaging.
VIDED and ADW increased the field of view (FOV) in the slice direction.
Spatial resolution improved by up to 60% (ADW) and 30% (VIDED) without extending scan time.

Conclusions:

VIDED and ADW enhance 3D DCE MR mammography image quality through improved spatial resolution, reduced crosstalk, and increased FOV.
VIDED achieves these improvements without longer scan times or multichannel receiver coils.