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Related Experiment Video

Updated: Jan 13, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

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Published on: June 18, 2021

Chronic spontaneous diploic hematoma.

José González-Tortosa¹, Javier Ros de San Pedro, Guillermo Parrilla

¹Servicio Regional de Neurocirugía, Hospital Universitario Virgen de la Arrixaca, 30120 El Palmar, Murcia, Spain. tortosa@ctv.es

Journal of Neurosurgery

|February 1, 2011

Summary

This study details a rare case of spontaneous diploic hematoma in a patient with neurofibromatosis Type 1. The hematoma was linked to abnormal venous drainage and vasculopathy, not trauma.

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Area of Science:

Neuroscience
Vascular Surgery
Genetics

Background:

Neurofibromatosis Type 1 (NF1) is a genetic disorder with diverse clinical manifestations.
Diploic hematomas are rare intracranial lesions typically associated with head trauma.

Observation:

A 23-year-old woman with NF1 stigmata presented with a spontaneous diploic hematoma of the left parietal bone.
Radiography revealed an osteolytic lesion with abnormal vascular markings.
Angiography showed an incidental carotid artery aneurysm and unusual venous drainage into diploic vessels.

Findings:

This is the first reported case of a non-traumatic diploic hematoma in a patient with NF1.
Abnormal venous drainage into the diploic space and vasculopathy causing venous obstruction are hypothesized as causative factors.

Implications:

This case expands the understanding of potential vascular complications in neurofibromatosis Type 1.
Highlights the importance of considering vascular abnormalities in NF1 patients presenting with intracranial lesions.