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Updated: Aug 11, 2026

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
[Microbial growth in parenteral nutrition. II. Effects of osmolality]
T Vílchez Medina1, C G Montero Herrero, A García Curiel
1Servicio de Farmacia, Hospital Universitario Virgen del Rocío, Sevilla.
Abstract:
Study on the behaviour of five microorganisms in different formulations of Parenteral Nutrition (PN) different from each other with regard to osmolarity. The organisms investigated were Staphylococcus aureus (ATCC (12600), Bacillus subtilis (ATCC 6051), Pseudomonas aeruginosa (ATCC 9027), Enterobacter cloacae (ATCC 13047) y Candida albicans (LSH 3156 D). It was observed no direct relation between microbial growth and osmolarity in PN. C. albicans showed the best growth in all the formulations tested, followed by E. Cloacae. The number of the other microorganisms is reduced, and in general, except B. subtilis grow or are reduced in a lesser extension when the glucose solutions added are at 30 or 40%.
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