Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Iodide-induced hypothyroidism in patients after thyroid resection.

O H Clark1, R R Cavalieri, C Moser

  • 1Surgical Service, Veterans Administration Medical Center, San Francisco, CA 94121.

European Journal of Clinical Investigation
|December 1, 1990
PubMed
Summary

Iodide administration can induce hypothyroidism even in normal thyroid tissue, not just in those with existing defects. This occurs due to increased thyroid-stimulating hormone (TSH) levels, impacting thyroid hormone production.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence of colorectal cancer in patients with Enterococcus faecalis blood stream infection: A nationwide study.

The Journal of infection·2025
Same author

Description and predictors of self-determination in males and females with fragile X syndrome on the verge of adulthood.

Journal of intellectual disability research : JIDR·2024
Same author

Long-term memory consolidation of new words in children with self-limited epilepsy with centro-temporal spikes.

Epilepsy & behavior : E&B·2024
Same author

Characterising the social interaction style of autism in young adult males with fragile X syndrome.

Journal of intellectual disability research : JIDR·2024
Same author

A comparative performance analysis of stand-alone, off-grid solar-powered sodium hypochlorite generators.

RSC advances·2022
Same author

Proximal caries infiltration - Pragmatic RCT with 4 years of follow-up.

Journal of dentistry·2021

Area of Science:

  • Endocrinology
  • Thyroidology

Background:

  • Iodide-induced hypothyroidism is a known condition.
  • The role of pre-existing thyroid defects in its development is unclear.

Purpose of the Study:

  • To investigate if iodide-induced hypothyroidism develops in normal thyroid tissue stimulated by elevated thyroid-stimulating hormone (TSH).

Main Methods:

  • Euthyroid patients (post-thyroidectomy and controls) received daily iodide (180 mg) for 3-4 months.
  • Serum TSH, T4, T3, and total iodine levels were monitored.

Main Results:

  • All subjects showed increased serum TSH during iodide administration.
  • TSH increased into the abnormal range in most post-thyroidectomy patients and some controls.

Related Experiment Videos

  • Five post-thyroidectomy patients developed mild hypothyroidism symptoms; T4/T3 levels decreased.
  • Two control patients showed slight decreases in T4.

    • Conclusions:

    • Iodide can induce hypothyroidism in TSH-stimulated normal thyroid tissue.
    • An intrinsic defect is not always required for iodide-induced hypothyroidism.