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Updated: Jun 4, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
[Iatrogenic pulmonary necrosis due to hyperselective chemotherapy]
P Vanelslander1, S Richard, Y Bouguerrouche
1Service d'Onco-Hématologie, Centre Hospitalier de Saint-Quentin, avenue Michel-de-l'Hospital, 02100 Saint-Quentin, France.
Central venous access systems are crucial for cancer management but can lead to serious complications. This case highlights a rare instance of pulmonary necrosis and abscess formation due to improper catheter placement, emphasizing the need for careful technique and monitoring.
Area of Science:
- Oncology
- Vascular Surgery
- Radiology
Background:
- Central venous access is essential for cancer treatment.
- Complications can arise from central venous access systems.
- Pulmonary complications are rare but severe.
Observation:
- A patient with B-cell lymphoma developed chest pain and pleural effusion post-chemotherapy.
- Imaging revealed a central venous catheter tip within a pulmonary artery branch.
- This led to consolidation and a lung abscess in the right lower lobe.
Findings:
- The central venous access system caused pulmonary necrosis and abscess formation.
- Despite removal of the device, the lung abscess persisted.
- Surgical intervention was required for resolution.
Implications:
- Proper technique during central venous access system placement is critical.
- Regular radiological surveillance is necessary to detect malposition.
- Early recognition and management of complications are vital for patient outcomes.
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