Related Experiment Video
Updated: Jun 4, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
Published on: May 17, 2024
[Primary myxoid mediastinal liposarcoma]
J-M Perotin1, G Deslee, D Perdu
1Service des Maladies Respiratoires, IFR 53, Hôpital Maison-Blanche, CHU de Reims, 45 rue Cognacq-Jay, 51100 Reims, France. jeanne-marie.perotin@etudiant.univ-reims.fr
Abstract:
Mediastinal liposarcomas (LPS) are rare tumours. We report a case of primary myxoid LPS in a 22-year-old woman suffering from cough, dyspnoea on exercise and asthenia for 3 weeks. Thoracic MRI showed a large tumour on the right side. After neoadjuvant chemotherapy, a complete resection was performed, followed by adjuvant thoracic irradiation. Eighteen months after the diagnosis, no sign of recurrence was detected. Mediastinal LPS include a heterogeneous group of bulky tumours, the progression of which depends on the histological type. The prognosis is dominated by the operability of the tumour. Adjuvant therapies are not established.