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Updated: Jun 4, 2026

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
Published on: August 8, 2014
The globe: infection, inflammation, and systemic disease.
Joseph Platnick1, Alison V Crum, Stephanie Soohoo
1Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.
Infections, inflammation, and systemic diseases can cause vision loss, ocular pain, or red eye. Accurate diagnosis relies on clinical examination and advanced imaging techniques for precise assessment.
Area of Science:
- Ophthalmology
- Medical Imaging
Background:
- Systemic diseases, infections, and inflammation can affect the eye.
- These conditions may lead to progressive vision loss, ocular pain, or red eye.
Purpose of the Study:
- To provide a comprehensive overview of pathologies affecting the globe.
- To highlight the role of clinical examination and imaging in diagnosis and assessment.
Main Methods:
- Review of clinical symptomatology.
- Selective use of diagnostic imaging: ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI).
Main Results:
- Pathologies range from silent vision loss to acute ocular symptoms.
- Imaging confirms diagnosis, assesses disease extent, and identifies systemic involvement.
Conclusions:
- Understanding differential diagnoses is crucial for interpreting imaging findings.
- Precise imaging analysis aids in managing diverse ocular pathologies.
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