Parvalbumin-positive CA1 interneurons are required for spatial working but not for reference memory.

Andrew J Murray1, Jonas-Frederic Sauer, Gernot Riedel

  • 1Institute of Medical Sciences, Foresterhill, University of Aberdeen, Aberdeen, UK.

Nature Neuroscience
|February 1, 2011
PubMed
Summary

Parvalbumin-positive interneurons are crucial for spatial working memory, but not spatial reference memory. Removing these specific neurons from the hippocampus did not affect one memory type but was essential for the other.