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Antibacterial activity of new synthesized amino-oxides and quaternary ammonium salts
V Cupková1, F Espersen, N Høiby
1Department of Biochemistry and Microbiology, Faculty of Pharmacy, Comenius University, Czechoslovakia.
Abstract:
An amino oxide and three quaternary ammonium salts were investigated for antimicrobial activity. All compounds had low MIC against gram positive bacteria. Despite high MIC the ammonium salts gave good killing of Pseudomonas aeruginosa in time kill experiments. These quaternary ammonium salts may be useful for disinfection as they are easily broken down in the environment.