Antimicrobial use in a small rural hospital

Insights

Antimicrobial use was audited in a rural Canadian hospital, revealing 33.7% of patients received antibiotics. While appropriate for children, 15% of adult treatments were inappropriate, particularly for skin and urinary tract infections.

Area of Science:

  • Clinical Pharmacy
  • Infectious Diseases
  • Healthcare Auditing

Background:

  • Antimicrobial stewardship is crucial for combating resistance and optimizing patient outcomes.
  • Understanding local antimicrobial prescribing patterns is essential for targeted interventions.
  • Rural healthcare settings may present unique challenges in antimicrobial use.

Purpose of the Study:

  • To audit and characterize the patterns of systemic antimicrobial utilization in a small rural Canadian hospital.
  • To assess the appropriateness of antimicrobial prescribing among hospitalized pediatric and adult patients.
  • To identify specific patient groups and infection types associated with inappropriate antimicrobial use.

Main Methods:

  • A retrospective audit of 252 hospitalized patients over a three-month period.
  • Data collection included patient demographics, diagnoses, prescribed antimicrobial agents, and treatment duration.
  • Prescribing appropriateness was evaluated based on established clinical guidelines.

Main Results:

  • 85 patients (33.7%) received systemic antimicrobials, comprising 19 children and 66 adults.
  • Respiratory infections were the most common indication for antimicrobial therapy in both age groups.
  • Ampicillin/amoxicillin was the most frequently prescribed agent; treatment was appropriate in all children but inappropriate in 15% of adults, notably for superficial skin and catheter-associated urinary tract infections.

Conclusions:

  • Significant antimicrobial use was observed, with a notable rate of inappropriate prescribing in adult patients.
  • Targeted interventions focusing on specific infections and patient populations are needed to improve antimicrobial stewardship.
  • Further investigation into the causes of inappropriate use is warranted to develop effective prevention strategies.

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