Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Economic aspects of geriatric care provided in family practice.

Canadian family physician Medecin de famille canadien·2010
Same author

Providence expands palliative care to meet patients' needs better.

Dimensions in health service·1986
Same author

Some changes of aging.

The Journal of otolaryngology·1986
Same author

Clinical assessment of the elderly patient.

Canadian Medical Association journal·1982
Same author

Geriatric patients with and without intellectual dysfunction: effectiveness of a standard rehabilitation program.

Archives of physical medicine and rehabilitation·1981
Same author

Rehabilitative and geriatric teaching programs: clinical efficacy in a skilled nursing facility.

Archives of physical medicine and rehabilitation·1980

Related Experiment Video

Updated: Jun 4, 2026

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
12:59

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

Maintaining ability in the elderly.

J E Schuman

    Canadian Family Physician Medecin De Famille Canadien
    |February 1, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Family physicians can improve older adults' quality of life by recognizing atypical disease symptoms and understanding aging's physiological changes. Focusing on prevention, rehabilitation, and fitness enhances geriatric care.

    More Related Videos

    Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
    06:52

    Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

    Published on: September 30, 2020

    Related Experiment Videos

    Last Updated: Jun 4, 2026

    Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
    12:59

    Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

    Published on: July 5, 2017

    Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
    06:52

    Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

    Published on: September 30, 2020

    Area of Science:

    • Geriatric Medicine
    • Family Practice
    • Internal Medicine

    Background:

    • Elderly patients frequently interact with family physicians, presenting opportunities for proactive health management.
    • Recognizing atypical disease presentation in older adults is crucial for accurate diagnosis.
    • Limited correlation between disease and disability, and under-reporting of conditions, complicate geriatric care.

    Purpose of the Study:

    • To highlight the role of family physicians in optimizing the health and well-being of elderly patients.
    • To emphasize the importance of understanding physiological changes associated with aging.
    • To advocate for a comprehensive approach to geriatric care.

    Main Methods:

    • Review of physiological changes in aging.
    • Analysis of atypical symptom presentation in elderly individuals.
    • Discussion of under-reporting of diseases in geriatric populations.

    Main Results:

    • Physiological changes of aging require specific consideration in medical practice.
    • Atypical symptoms are common in elderly patients with diseases.
    • Geriatric diseases are frequently under-reported, impacting timely intervention.

    Conclusions:

    • Family physicians play a vital role in enhancing the quality of life for elderly patients.
    • Judicious medical treatment, prevention, rehabilitation, and fitness are key components of effective geriatric care.
    • Understanding the unique aspects of aging is essential for maximizing patient ability and outcomes.