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Related Concept Videos

Pleural Effusion II: Symptoms and Management01:28

Pleural Effusion II: Symptoms and Management

Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's criteria,...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Inhalation Anthrax01:25

Inhalation Anthrax

Anthrax is a zoonotic disease caused by Bacillus anthracis, a Gram-positive, spore-forming bacterium. It primarily affects herbivorous animals but can be transmitted to humans through skin contact, ingestion, or inhalation of spores.Cutaneous anthrax, the most common form, typically results from direct contact with bacterial spores through skin abrasions and is generally less severe. Gastrointestinal anthrax results from eating undercooked or contaminated meat. It affects the mouth, throat, or...

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Related Experiment Video

Updated: Jun 4, 2026

A Pleural Effusion Model in Rats by Intratracheal Instillation of Polyacrylate/Nanosilica
03:32

A Pleural Effusion Model in Rats by Intratracheal Instillation of Polyacrylate/Nanosilica

Published on: April 12, 2019

Isoniazid causing pleural effusion.

S K Singh1, Z Ahmad, D K Pandey

  • 1Department of Tuberculosis and Respiratory Diseases, JN Medical College, AMU, Aligarh, UP, India.

Indian Journal of Pharmacology
|February 1, 2011
PubMed
Summary
This summary is machine-generated.

Isoniazid, a key tuberculosis drug, can cause pleural effusion, a fluid buildup in the lungs. Discontinuing isoniazid resolved the patient's effusion, highlighting its potential adverse effect.

Keywords:
Antitubercular drugisoniazidparadoxical responsepleural effusion

Related Experiment Videos

Last Updated: Jun 4, 2026

A Pleural Effusion Model in Rats by Intratracheal Instillation of Polyacrylate/Nanosilica
03:32

A Pleural Effusion Model in Rats by Intratracheal Instillation of Polyacrylate/Nanosilica

Published on: April 12, 2019

Area of Science:

  • Medical research
  • Clinical case study

Background:

  • Isoniazid (INH) is a primary medication for tuberculosis treatment.
  • Spinal tuberculosis requires prolonged antitubercular therapy.

Purpose of the Study:

  • To report a rare case of drug-induced pleural effusion.
  • To identify isoniazid as the causative agent for pleural effusion in a patient with spinal tuberculosis.

Main Methods:

  • Case report detailing clinical presentation and treatment.
  • Observation of patient's response to drug discontinuation.

Main Results:

  • A patient developed pleural effusion two months into antitubercular treatment.
  • Discontinuation of isoniazid led to the resolution of the pleural effusion.

Conclusions:

  • Isoniazid can induce pleural effusion as an adverse effect.
  • Early recognition and drug withdrawal are crucial for managing isoniazid-induced pleural effusion.