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Related Experiment Video

Updated: Jun 4, 2026

Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling
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Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

Published on: May 31, 2024

MR angiography and arterial spin labelling.

David Thomas1, Jack Wells

  • 1Department of Medical Physics and Bioengineering, University College London, London, UK. thomas@medphys.ucl.ac.uk

Methods in Molecular Biology (Clifton, N.J.)
|February 1, 2011
PubMed
Summary

Magnetic Resonance Imaging (MRI) enables non-invasive visualization and measurement of blood flow. Techniques like MR angiography (MRA) and arterial spin labelling (ASL) quantify blood velocity and tissue perfusion without contrast agents.

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Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
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Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling
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Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

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Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
12:29

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling

Published on: May 30, 2011

Area of Science:

  • Medical Imaging
  • Cardiovascular Physiology
  • Radiology

Background:

  • Magnetic Resonance Imaging (MRI) is a powerful, non-invasive tool for visualizing and quantifying physiological processes.
  • Accurate assessment of blood flow is crucial for diagnosing and monitoring various medical conditions.
  • Traditional methods for blood flow assessment may be invasive or lack quantitative precision.

Purpose of the Study:

  • To describe the technical basis and practical implementation of non-invasive MRI techniques for blood flow assessment.
  • To highlight the quantitative and non-contrast-requiring nature of MR angiography (MRA) and arterial spin labelling (ASL).
  • To emphasize the utility of these methods in evaluating arterial vasculature and tissue perfusion.

Main Methods:

  • MR angiography (MRA) for imaging arterial vessels and measuring blood velocities.
  • Arterial spin labelling (ASL) for quantifying blood perfusion into tissues at the capillary level.
  • Focus on the technical principles and practical application of these MRI sequences.

Main Results:

  • MRI techniques, specifically MRA and ASL, provide non-invasive visualization of blood vessels.
  • These methods allow for quantitative measurement of blood flow parameters, including velocity and perfusion.
  • The non-invasive nature eliminates the need for contrast agents, enhancing patient safety and accessibility.

Conclusions:

  • MRA and ASL are valuable, non-invasive MRI techniques for comprehensive blood flow assessment.
  • These methods offer quantitative insights into arterial hemodynamics and tissue nutrient supply.
  • The absence of contrast agents makes these techniques particularly advantageous for widespread clinical application.