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Multiple interatrial electrical connection after heart transplantation.

Pablo Peñafiel-Verdú1, Mariela Salar-Alcaraz, Asunción Fernández-Fernández

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A heart transplant recipient experienced atrial tachycardia due to multiple conduction pathways. Ablation successfully targeted three distinct connections, resolving the arrhythmia.

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Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiac Surgery

Background:

  • Post-heart transplantation atrial tachycardia is a known complication.
  • Identifying the arrhythmogenic substrate in complex cardiac anatomies can be challenging.

Observation:

  • A 62-year-old heart transplant recipient presented with regular atrial tachycardia 6 years post-transplant.
  • Electrophysiologic evaluation revealed an atrial arrhythmia with 2:1 conduction from the recipient to the donor atrium.
  • Initial electroanatomical mapping was confusing, suggesting alternant conduction through multiple breakthroughs.

Findings:

  • The electroanatomical map was divided into two concordant maps, identifying two successful ablation sites.
  • A third distinct arrhythmogenic connection was subsequently detected and successfully ablated.
  • This approach resolved the complex atrial tachycardia in the heart transplant recipient.

Implications:

  • This case highlights the potential for multiple arrhythmogenic pathways after heart transplantation.
  • Advanced electrophysiological mapping techniques are crucial for diagnosing and treating complex arrhythmias in transplant patients.
  • Successful ablation of multiple connections can restore sinus rhythm and improve outcomes in heart transplant recipients.