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Update on the management of acute pharyngitis in children
Marta Regoli1, Elena Chiappini, Francesca Bonsignori
1Department of Sciences for Woman and Child's Health, University of Florence, Florence, Italy. marta.regoli@hotmail.it
Insights
Management of streptococcal pharyngitis in children lacks consensus. While some advocate for microbiological testing and antibiotics to prevent complications, others favor a judicious antibiotic approach for selected cases, highlighting the low incidence of preventable issues.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Streptococcal pharyngitis is a common global pediatric illness.
- Current management strategies for streptococcal pharyngitis lack universal agreement.
- Debate exists regarding the necessity of routine microbiological investigation and antibiotic treatment.
Purpose of the Study:
- To explore the divergent approaches in managing streptococcal pharyngitis in children.
- To discuss the rationale behind routine testing versus selective antibiotic use.
- To review antibiotic treatment guidelines and alternatives.
Main Methods:
- Literature review of current management guidelines and expert opinions.
- Analysis of the benefits and drawbacks of microbiological investigations.
- Evaluation of antibiotic efficacy and resistance patterns.
Main Results:
- Significant disagreement persists on the necessity of microbiological testing for suspected streptococcal pharyngitis.
- The number needed to treat to prevent one complication is substantial, questioning routine antibiotic use.
- Penicillin remains the first-line treatment, with amoxicillin as a palatable alternative; macrolides and cephalosporins have specific indications.
Conclusions:
- The management of streptococcal pharyngitis requires careful consideration of potential complications versus the risks of antibiotic overuse.
- Selective antibiotic therapy, guided by clinical assessment and judicious testing, is a viable approach.
- Standardized guidelines are needed to optimize patient outcomes and promote antimicrobial stewardship.
Abstract:
Streptococcal pharyngitis is a very common pathology in paediatric age all over the world. Nevertheless there isn't a joint agreement on the management of this condition. Some authors recommend to perform a microbiological investigation in suspected bacterial cases in order to treat the confirmed cases with antibiotics so to prevent suppurative complications and acute rheumatic fever. Differently, other authors consider pharyngitis, even streptococcal one, a benign, self-limiting disease. Consequently they wouldn't routinely perform microbiological tests and, pointing to a judicious use of antibiotics, they would reserve antimicrobial treatment to well-selected cases. It has been calculated that the number of patients needed to treat to prevent one complication after upper respiratory tract infections (including sore throat), was over 4000. Even the use of the Centor score, in order to evaluate the risk of streptococcal infection, is under debate and the interpretation of the test results may vary considerably. Penicillin is considered all over the world as first line treatment, but oral amoxicillin is also accepted and, due to its better palatability, can be a suitable option. Macrolides should be reserved to the rare cases of proved allergy to β-lactams. Cephalosporins can be used in patients allergic to penicillin (with the exception of type I hypersensibility) and have been also proposed to treat the relapses.
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