Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Three-Dimensional Microscopy in Microbiology01:28

Three-Dimensional Microscopy in Microbiology

Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beech latewood density as a proxy for temperature reconstruction.

Science advances·2026
Same author

Rosy Discolouration in an Alpine Chapel: Beyond Salt Dependence.

Microbial ecology·2026
Same author

Biomimetic characterization by micro-computed tomography (μCT) of 3D hollow fibre membrane network bioreactors for tissue engineering.

Biomaterials science·2026
Same author

Predicting dialyzer fiber blocking is hard due to high intrapatient variability and limited utility of thrombin generation markers.

Scientific reports·2026
Same author

Analysis and Comparison of Natural Shear and Induced Tensile Fractures for Caprock Leakage Assessment.

Transport in porous media·2026
Same author

Exposure to 5G-NR electromagnetic fields affects larval development of Aedes aegypti mosquito.

Scientific reports·2025

Related Experiment Video

Updated: Jun 4, 2026

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
05:05

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration

Published on: November 23, 2019

Three-dimensional analysis of high-resolution X-ray computed tomography data with Morpho+.

Loes Brabant1, Jelle Vlassenbroeck, Yoni De Witte

  • 1Department of Physics and Astronomy, Ghent University, Proeftuinstraat 86, B-9000 Ghent, Belgium. Loes.Brabant@UGent.be

Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
|February 2, 2011
PubMed
Summary

Morpho+ is a new 3D analysis software package developed for high-resolution X-ray computed tomography (CT) data. It provides advanced algorithms for microstructure investigation, enabling quantitative results for diverse scientific research.

More Related Videos

Correlative Microscopy for 3D Structural Analysis of Dynamic Interactions
13:43

Correlative Microscopy for 3D Structural Analysis of Dynamic Interactions

Published on: June 24, 2013

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography
02:42

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography

Published on: January 17, 2025

Related Experiment Videos

Last Updated: Jun 4, 2026

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
05:05

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration

Published on: November 23, 2019

Correlative Microscopy for 3D Structural Analysis of Dynamic Interactions
13:43

Correlative Microscopy for 3D Structural Analysis of Dynamic Interactions

Published on: June 24, 2013

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography
02:42

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography

Published on: January 17, 2025

Area of Science:

  • Materials Science
  • Computer Science
  • Imaging Technology

Background:

  • Three-dimensional (3D) analysis is crucial for quantitative results from 3D datasets.
  • Advancements in 3D imaging necessitate flexible analysis packages with advanced algorithms.
  • High-resolution X-ray computed tomography (CT) requires specialized software for microstructure analysis.

Purpose of the Study:

  • To develop an in-house analysis software package, Morpho+, to meet the specific needs of diverse research groups.
  • To provide a comprehensive suite of high-performance 3D operations for quantitative analysis of CT data.
  • To facilitate nondestructive investigation of material microstructures using high-resolution X-ray CT.

Main Methods:

  • Development of the Morpho+ software package at the Centre for X-ray Tomography (UGCT).
  • Implementation of advanced algorithms for object segmentation, separation, and parameterization.
  • Integration of interactive visualization and user-friendly interface for data analysis.

Main Results:

  • Morpho+ offers an extensive set of 3D operations including segmentation, separation, and parameterization (e.g., orientation, diameter, sphericity).
  • The software can extract 3D geometrical representations like surface meshes or skeletons for further modeling.
  • Algorithms demonstrate relatively short processing times for large datasets.

Conclusions:

  • Morpho+ provides scientists with essential quantitative results for high-resolution X-ray CT research.
  • The software supports nondestructive investigation of material microstructures across various scientific disciplines.
  • Morpho+ enhances the utility of X-ray CT as a powerful research tool.