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Identification of novel alternative splicing variants of interferon regulatory factor 3

Yong Li1, Xiuhua Hu, Yuqin Song

  • 1Key laboratory of Carcinogenesis and Translational Research, Department of Genesis, Peking University School of Oncology , Beijing Cancer Hospital & Institute, Beijing, PR China.

Biochimica Et Biophysica Acta
|February 2, 2011
PubMed

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Alternative RNA Splicing02:18

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R stands for...
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