The APA and the rise of pediatric generalist network research

Richard Wasserman1, Janet R Serwint, Nathan Kuppermann

  • 1Department of Pediatrics, University of Vermont College of Medicine, 89 Beaumont Ave., Burlington, VT 05405, USA. richard.wasserman@uvm.edu

Academic Pediatrics
|February 2, 2011
PubMed

Insights

Academic Pediatric Association research networks have improved child health for over 30 years. These collaborations generate vital knowledge in general pediatrics, emergency care, continuity, and inpatient settings.

Area of Science:

  • Pediatric Health Services Research
  • Multi-institutional Pediatric Networks

Background:

  • The Academic Pediatric Association (APA) has fostered multi-institutional research for over three decades.
  • Individual APA members have been instrumental in establishing formal research networks.
  • These networks focus on generalist contexts in pediatric care.

Purpose of the Study:

  • To review the history, accomplishments, and future directions of four major pediatric generalist research networks.
  • To summarize common themes, strengths, challenges, and opportunities in pediatric network research.

Main Methods:

  • Review of historical data and achievements of four established pediatric research networks.
  • Analysis of commonalities, strengths, weaknesses, and future prospects of these networks.

Main Results:

  • Four prominent generalist networks exist: PROS, PECARN, CORNET, and PRIS.
  • These networks have a significant track record of generating knowledge to improve child health and healthcare.
  • The review synthesizes common elements and future outlooks for pediatric network research.

Conclusions:

  • Pediatric generalist research networks are crucial for advancing child health.
  • Sustained collaboration and addressing network challenges are key to future success.
  • These networks offer valuable insights into improving pediatric healthcare delivery.

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Contemporary Psychology01:29

Contemporary Psychology

Psychology explores human behavior and mental processes through various lenses, each offering unique insights. This overview examines key subfields, including biopsychology, evolutionary, developmental, personality, and social psychology, highlighting their approaches and contributions to understanding complex human behaviors.
Biopsychology
Biopsychology, also known as biological psychology or behavioral neuroscience, focuses on the biological underpinnings of behavior and mental processes. It...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Current Trends in Nursing II01:30

Current Trends in Nursing II

Trends in nursing are multifactorial and associated with changes in society, within the nursing profession, and in other professions. Notably, telehealth and remote nursing contribute to successful healthcare delivery for numerous patients and help reduce stress for nurses due to nursing shortages. Nurses can reach patients, monitor their conditions, and interact with them using computers, audio, visual accessories, and telephones—for example, remote patient monitoring systems. Likewise,...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...