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Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
Published on: February 16, 2018
[Spectroscopy study of binding mechanisms and molecular recognition of class-specific molecularly imprinted polymer
Yong-xin She1, Miao Wang, Xiao-mei Shi
1Institute of Quality Standards and Testing Technology for Agri-Products, Chinese Academy of Agricultural Sciences, Key Laboratory for Agri-Products Quality and Food Safety, Chinese Academy of Agricultural Sciences, Beijing 100081, China. 0891syx@163.com
Abstract:
A novel class-specific molecularly imprinted polymer (MIP) beads for sulfonylurea herbicides was synthesized by precipitation polymerization using chlorsulfuron as the template molecule, 2-(diethylamino) ethyl methacrylate (DEAEMA) as the functional monomer, and trimethylolpropane trimethacrylate (TRIM) as the cross-linker. The mechanisms of recognition of MIP beads to the template molecule were evaluated by UV-spectrum and FTIR in the choosing and optimizing polymerization system experiment. The results showed that MIP beads contained the group which could interact with template molecule and its analogue by the hydrogen bonding specifically.

