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Giant glioependymal cyst in an infant

Ryoma Morigaki1, Kiyohito Shinno, Kyong-Hon Pooh

  • 1Department of Neurosurgery, National Hospital Organization, Kagawa Children's Hospital, Kagawa, Japan. morigakiryoma@hotmail.com

Journal of Neurosurgery. Pediatrics
|February 3, 2011
PubMed

Insights

A giant glioependymal cyst in an infant was successfully treated with endoscopic fenestration. This case suggests the tela choroidea as the origin of these rare brain cysts.

Area of Science:

  • Neuroscience
  • Pediatric Neurosurgery
  • Pathology

Background:

  • Glioependymal cysts are rare intracranial lesions.
  • Their precise origin, particularly in infants, remains debated.
  • Potential origins include the tela choroidea or ependymal/glial elements.

Observation:

  • A 35-month-old girl presented with truncal ataxia and hydrocephalus.
  • MRI revealed a giant cystic mass spanning the anterior and posterior cranial fossae, obstructing the sylvian aqueduct.
  • Endoscopic fenestration of the cyst was performed.

Findings:

  • Histochemical and immunohistochemical analysis confirmed the lesion as a glioependymal cyst.
  • Post-operative MRI suggested the cyst originated from the tela choroidea.
  • A 5-year follow-up showed no recurrence and complete recovery.

Implications:

  • This case supports the tela choroidea as a potential origin for glioependymal cysts.
  • Endoscopic fenestration is a viable treatment for giant glioependymal cysts causing hydrocephalus.
  • Further research into the embryological development of glioependymal cysts is warranted.

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