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Related Concept Videos

Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma

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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
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Occupational asthma in professional cleaning work: a clinical study.

R Mäkelä1, P Kauppi, K Suuronen

  • 1Occupational Medicine, Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, FI-00250 Helsinki, Finland.

Occupational Medicine (Oxford, England)
|February 3, 2011
PubMed
Summary

Occupational asthma (OA) in cleaners is often caused by chemicals and molds. This study highlights molds as a newly identified trigger for OA in this profession.

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Area of Science:

  • Occupational Medicine
  • Pulmonology
  • Environmental Health

Background:

  • Epidemiological studies indicate a higher risk of asthma among professional cleaners.
  • Limited large-scale clinical data exists on occupational asthma (OA) in this sector.
  • This study addresses the gap by analyzing cases from a specialized occupational health clinic.

Purpose of the Study:

  • To document and analyze cases of occupational asthma (OA) diagnosed in cleaning workers.
  • To identify the specific triggers and exposure durations associated with OA in this cohort.
  • To investigate the role of both chemical and biological agents in cleaner-related OA.

Main Methods:

  • Diagnosis of OA was based on detailed patient history, including occupational exposure.
  • Pulmonary function tests, such as forced expiratory volume in 1 second (FEV1) and peak expiratory flow (PEF), were utilized.
  • Specific challenge tests were conducted to confirm allergen or irritant sensitivity.

Main Results:

  • The study included 20 female cleaning workers, with a mean age of 48.8 years.
  • Symptoms of OA appeared after an average of 14.3 years of cleaning work.
  • Triggers included chemicals (45%), such as ethanolamines and chloramine-T, and molds (55%), predominantly Aspergillus fumigatus.

Conclusions:

  • Occupational asthma in cleaners can be triggered by a range of chemicals beyond typical cleaning agents.
  • Molds, particularly Aspergillus fumigatus, are identified as a significant and previously under-recognized cause of OA in this occupational group.
  • This research underscores the need for comprehensive exposure assessment and control measures in cleaning environments.