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Allergic Reactions

Allergic Reactions

Allergic Reactions: Anaphylaxis

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

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Assessment of Lymphocyte Migration in an Ex Vivo Transmigration System

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Allergy and occupation.

Canadian Family Physician Medecin De Famille Canadien

|February 3, 2011

Summary

Occupational exposure can cause skin and respiratory sensitization, leading to allergic reactions like late and dual asthmatic responses. Early identification by physicians is crucial for managing worker health.

Area of Science:

Occupational medicine
Allergology
Immunology

Background:

The skin and respiratory tract are vulnerable to occupational sensitizers.
Allergic reactions in these sites can present diagnostic challenges, particularly late and dual asthmatic reactions.

Purpose of the Study:

To discuss the responses of the skin and respiratory tract to occupational sensitizers.
To highlight diagnostic difficulties associated with late and dual asthmatic reactions.
To provide data on the incidence and prevalence of occupational allergic reactions.

Main Methods:

Review of existing literature on occupational skin and respiratory sensitization.
Inclusion of estimated frequencies for occupational allergic reactions.
Compilation of tables listing major industrial sensitizing agents.

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Main Results:

Occupational exposure to various agents can lead to skin and respiratory sensitization.
Late and dual asthmatic reactions are noted as potential diagnostic challenges.
Estimated frequencies of occupational allergic reactions are presented, with tables of common sensitizers.

Conclusions:

A detailed occupational history is essential for identifying sensitizing agents.
Family physicians play a key role in identifying and documenting workplace exposures that cause sensitization.
Awareness of occupational allergic reactions is important for healthcare providers.