Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Diphtheria

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...

Infectious Diseases and Their Occurrence

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...

Viral Recombination

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.

Sexually Transmitted Infections

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...

Trichomoniasis

Trichomoniasis

Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.

Immunodeficiency Diseases

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The cost of providing office services in family medicine: a survey of Saskatchewan family physicians 1980-1981.

Canadian family physician Medecin de famille canadien·2011

Same author

A surviving child with complete proximal tracheal atresia.

Canadian family physician Medecin de famille canadien·2011

Same author

A Mother's Reactions to an Infant With an Abnormality.

Canadian family physician Medecin de famille canadien·2011

Same author

Obstructive jaundice: a case of idiopathic cholestasis.

Canadian family physician Medecin de famille canadien·2011

Same author

Migraine as seen by the ophthalmologist.

Southern medical journal·2010

Same author

Case management in a retirement community.

Nursing administration quarterly·1993

Search research articles

Related Experiment Video

Updated: Jun 4, 2026

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

Published on: April 14, 2011

When Infections Co-exist: Infectious Mono and Diphtheria.

K Haight, F A Holden

Canadian Family Physician Medecin De Famille Canadien

|February 3, 2011

Summary

This case study highlights a patient initially diagnosed with infectious mononucleosis who developed a rash after amoxicillin treatment. The patient also had a concurrent diphtheria infection, emphasizing careful antibiotic selection.

Area of Science:

Infectious Diseases
Clinical Microbiology

Background:

Infectious mononucleosis is a common viral illness.
Diphtheria is a serious bacterial infection caused by Corynebacterium diphtheriae.

Purpose of the Study:

To report a case of infectious mononucleosis with a coincidental pharyngeal infection of toxigenic C. diphtheriae.
To discuss the appropriate antibiotic management in such cases.

Main Methods:

Clinical presentation and patient history.
Laboratory investigations including throat cultures.
Monitoring of patient's response to antibiotic treatment.

Main Results:

Patient presented with symptoms suggestive of infectious mononucleosis.

More Related Videos

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

Published on: September 28, 2022

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

Related Experiment Videos

Last Updated: Jun 4, 2026

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

Published on: April 14, 2011

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

Published on: September 28, 2022

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

Throat swab culture confirmed a toxigenic strain of C. diphtheriae.

Patient developed a rash, likely an amoxicillin-induced reaction.

Conclusions:

Antibiotics are not indicated for infectious mononucleosis unless bacterial co-infections are present.
Ampicillin-amoxicillin should be avoided in patients with suspected infectious mononucleosis due to potential adverse reactions.
Careful consideration of antibiotic choice is crucial when bacterial pathogens are identified.