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These markers indicate stress or strain on the heart muscle:
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Related Experiment Video

Updated: Jun 4, 2026

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood

Published on: April 28, 2016

Ghrelin and cardiovascular diseases.

Gaigai Zhang¹, Xinhua Yin, Yongfen Qi

¹Cardiology Department, the First Affiliated Hospital of Harbin Medical University, Harbin,P. R. China 150081.

Current Cardiology Reviews

|February 3, 2011

Summary

Ghrelin, a peptide hormone, plays a vital role in regulating appetite and has significant cardiovascular protective effects. Research indicates its potential for treating cardiovascular diseases.

Keywords:

Ghrelin cachexia.cardiomyopathy coronary artery disease heart failure hypertension

Related Experiment Videos

Last Updated: Jun 4, 2026

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood

Published on: April 28, 2016

Area of Science:

Endocrinology
Cardiovascular Physiology

Background:

Ghrelin is a peptide hormone and the endogenous ligand for the growth hormone secretagogue receptor.
Initially known for stimulating growth hormone release, ghrelin is now recognized for its widespread presence and diverse functions in various organs, including the cardiovascular system.

Purpose of the Study:

To review the existing evidence on the cardiovascular effects of ghrelin.
To explore the cardiovascular functions, plasma level variations in disease, protective mechanisms, and therapeutic potential of ghrelin.

Main Methods:

Review of existing scientific literature on ghrelin and its cardiovascular effects.
Analysis of studies investigating ghrelin's direct and indirect impacts on the cardiovascular system.

Main Results:

Ghrelin and its receptors are distributed in cardiovascular tissues, mediating effects directly on the heart and vasculature.
Exogenous ghrelin administration demonstrates beneficial effects such as vasodilation, coronary artery constriction, improved endothelial function, and inhibition of myocardial apoptosis.
Ghrelin shows potential in lowering blood pressure, regulating atherosclerosis, protecting against ischemia/reperfusion injury, and improving outcomes in myocardial infarction and heart failure.

Conclusions:

Ghrelin exhibits significant cardiovascular protective effects beyond its role in growth hormone release.
Ghrelin's multifaceted actions suggest promising therapeutic opportunities for cardiovascular medicine.