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Pure red cell aplasia associated with essential thrombocythemia (a case report)
R Sarode1, P Bambery, N Marwaha
1Department of Hematology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Indian Journal of Cancer
|September 1, 1990
Abstract:
A rare case of erythroblastopenia associated with essential thrombocythemia (ET) is described. The patient had markedly elevated platelet count (5200 x 10(9)/1) and significant platelet dysfunction leading to extensive soft tissue and gastrointestinal hemorrhage. There was paucity of erythroid precursors in the bone marrow - a feature hitherto undescribed in ET. The thrombocytosis responded to well busulphan therapy but patient succumbed to fulminant infection consequent upon drug induced neutropenia.