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Long-term Potentiation01:35

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Long-term Potentiation01:25

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when presynaptic neurons...
System of Memory01:23

System of Memory

Memory is categorized into three major systems: sensory memory, short-term memory (STM), and long-term memory (LTM). These systems differ in their capacity and the duration for which they can hold information. Sensory memory captures raw sensory input from the environment, holding it for just a few seconds or less. For example, on hearing a brief, loud sound, like a car horn honking, the sound seems to linger in the mind for a moment even after it stops. This is an instance of sensory memory...
Long-Term Memory01:18

Long-Term Memory

Long-term memory is a relatively permanent type of memory, capable of storing vast amounts of information over extended periods. Its storage capacity is generally considered unlimited.
Long-term memory can be categorized into two primary types: explicit and implicit memory. Explicit memory, also known as declarative memory, involves the conscious recollection of information that we deliberately try to remember, recall, and articulate. This type of memory encompasses specific facts, events, and...
Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
Higher Mental Functions of Brain: Learning and Memory01:26

Higher Mental Functions of Brain: Learning and Memory

Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or playing an...

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Related Experiment Video

Updated: Jun 4, 2026

Assessment of Memory Function in Pilocarpine-induced Epileptic Mice
13:34

Assessment of Memory Function in Pilocarpine-induced Epileptic Mice

Published on: June 4, 2020

Recognition memory: One-component strength functions In the "short-term to long-term transition region".

A V Reed1

  • 1University of Oregon, 97403, Eugene, Oregon.

Memory & Cognition
|February 3, 2011
PubMed
Summary
This summary is machine-generated.

This study on memory storage found that retention interval manipulations did not support separate short-term and long-term memory strengths. A single-trace model effectively explains memory strength data, challenging dual-trace theories.

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Related Experiment Videos

Last Updated: Jun 4, 2026

Assessment of Memory Function in Pilocarpine-induced Epileptic Mice
13:34

Assessment of Memory Function in Pilocarpine-induced Epileptic Mice

Published on: June 4, 2020

Memorization-Based Training and Testing Paradigm for Robust Vocal Identity Recognition in Expressive Speech Using Event-Related Potentials Analysis
05:48

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Area of Science:

  • Cognitive Psychology
  • Neuroscience
  • Memory Research

Background:

  • Understanding the mechanisms of memory storage is crucial for cognitive science.
  • Distinguishing between short-term and long-term memory systems has been a long-standing debate.
  • Previous models often proposed simultaneous short-term and long-term memory traces.

Purpose of the Study:

  • To investigate whether short-term and long-term memory strengths are independently adjustable.
  • To evaluate the explanatory power of single-trace versus dual-trace memory models.
  • To analyze memory strength functions in relation to retention intervals.

Main Methods:

  • Experimental manipulation of the upper bound of retention intervals (30 seconds vs. 2 minutes).
  • Obtaining accurate strength functions of retention time.
  • Fitting data with one-component and two-component equations derived from different memory theories.

Main Results:

  • Experimental manipulation failed to provide evidence for independent adjustment of short-term and long-term storage strengths.
  • Both one-component and two-component equations equally fitted the obtained strength functions.
  • A one-component theory, postulating sequential active and passive storage, explained the data well.

Conclusions:

  • The findings challenge theories positing simultaneous short-term and long-term memory traces.
  • A single-trace model, involving sequential processing, appears sufficient to explain memory strength data.
  • Further discussion is needed regarding the postulate of a single post-attentional trace versus dual traces.