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Updated: Aug 12, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[The pathogenesis of nasal mucosa polyps, studied with histochemical detection of phenol oxidase (E. C. 1.14.18.1)]
V H Schmidt1, D Krell, R Krell
1Institut für Biochemie, Bereiches Medizin, Martin-Luther-Universität, Halle, Deutschland.
Abstract:
There were investigated polyps of the nasal mucous membrane with the histological diagnosis: allergic-hyperergic, lympho-plasma cellular, and angioma-like. Using the phenol oxidase reaction, it was possible to integrate the allergic-hyperergic and the lympho-plasma cellular polyps into the pathologic course of cell mediated immunological defence reactions in which the eosinophilic granulocytes have an essential role. The eosinophils are typical for the immunological character of the defense reaction.

