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Formyl-methanofuran synthesis in Methanobacterium thermoautotrophicum
T A Bobik1, A A DiMarco, R S Wolfe
1Department of Microbiology, University of Illinois, Urbana 61801.
FEMS Microbiology Reviews
|December 1, 1990
Abstract:
The initial step of methanogenesis from CO2 is the formation of formyl-methanofuran (formyl-MFR) from methanofuran (MFR), CO2 and H2. The enzymology of this novel type of CO2 fixation reaction has been difficult to study because formyl-MFR synthesis is subject to a complex activation. Recently, however, a number of advances have made questions regarding formyl-MFR synthesis more approachable.