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Updated: Jun 4, 2026

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
Published on: July 28, 2022
[Nutrition of the preterm infant]
A Lapillonne1, H Razafimahefa, V Rigourd
1Université Paris Descartes, 75006 Paris, France. alexandre.lapillonne@nck.aphp.fr
Abstract:
The quality of nutritional support impacts not only the growth and quality of growth of preterm infants, but also all aspects of their development. In order to provide optimal nutrition, two main rules should be followed: optimise early parenteral nutrition and introduce appropriate enteral nutrition preferably with the mother's milk as early as possible. Recommendations have recently increased early energy and protein intake. The term "aggressive nutrition" has been introduced to qualify these changes, but we prefer the term "optimal nutrition," which more precisely reflects the physiology and needs of the preterm infant. Specific efforts should be continued to improve physician training in neonatal nutrition and to facilitate the dissemination of the most recent recommendations. Standardization of nutritional protocols in neonatal units should be promoted as a way to improve overall nutritional care. A full field of research remains open to determine the most effective nutritional strategy for preterm infants in order to maximize their growth and development.
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