[Pregnancy with Implanon: a report on three cases]

Area of Science:

• Reproductive Health
• Pharmacology
• Contraception

Background:

• The etonogestrel contraceptive implant (Implanon) is a long-acting reversible contraceptive method.
• Pregnancies with contraceptive implants necessitate investigation into potential failure mechanisms.

Observation:

• Three cases of Implanon treatment failure resulting in pregnancy were analyzed.
• No predisposing factors like high Body Mass Index or hepatic-inducing therapy were identified in these cases.

Findings:

• Etonogestrel levels were positive in two of the three cases.
• In the third case, the implant was not detected by palpation or ultrasonography, suggesting potential misplacement or migration.
• True contraceptive failure was considered in two cases, while the third remains uncertain due to detection issues.

Implications:

• These findings highlight the rare but possible risk of contraceptive failure with etonogestrel implants.
• Pregnancies associated with Implanon warrant thorough investigation and reporting to pharmacovigilance systems.
• Further attention is needed for monitoring and reporting adverse events related to etonogestrel implants.