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Updated: Jun 4, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
Published on: September 12, 2011
Structural MRI in autism spectrum disorder
Rong Chen1, Yun Jiao, Edward H Herskovits
1Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. rong.chen@uphs.upenn.edu
Abstract:
Magnetic resonance (MR) examination provides a powerful tool for investigating brain structural changes in children with autism spectrum disorder (ASD). We review recent advances in the understanding of structural MR correlates of ASD. We summarize findings from studies based on voxel-based morphometry, surface-based morphometry, tensor-based morphometry, and diffusion-tensor imaging. Finally, we discuss diagnostic models of ASD based on MR-derived features.
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