Related Experiment Video
Updated: Jun 4, 2026

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
Published on: November 28, 2018
Cardiac murmurs in childhood
Insights
Clinical skills can differentiate innocent heart murmurs from organic ones. This guide details distinguishing features to avoid unnecessary medical referrals and patient concern.
Area of Science:
- Cardiology
- Pediatric Cardiology
Background:
- Distinguishing innocent heart murmurs from pathological organic murmurs is crucial in clinical practice.
- Misdiagnosis can lead to unnecessary patient anxiety and referrals.
Purpose of the Study:
- To outline clinical methods for differentiating innocent heart murmurs from various organic murmurs.
- To provide clinicians with tools for accurate diagnosis using only clinical skills.
Main Methods:
- Differentiation based on the behavior of the second heart sound.
- Assessment of murmur length, radiation, and response to specific maneuvers.
- Utilizing blood pressure recordings for specific murmur types.
Main Results:
- Pulmonary flow murmurs distinguished from atrial septal defect/pulmonary stenosis by second heart sound.
- Parasternal vibratory murmurs differentiated from ventricular septal defect.
- Venous hums identified and separated from patent ductus arteriosus.
- Supraclavicular murmurs distinguished from carotid bruit, aortic stenosis, and coarctation.
Conclusions:
- Clinical skills are sufficient for identifying innocent heart murmurs.
- Accurate differentiation obviates unnecessary patient concern and referrals.
- A systematic approach using auscultation and simple maneuvers aids diagnosis.
Abstract:
Innocent heart murmurs can be identified and distinguished from organic murmurs using only clinical skills. Pulmonary flow murmurs may be differentiated from those of atrial septal defect or pulmonary stenosis by the behavior of the second heart sound, parasternal vibratory murmurs from ventricular septal defect, aortic stenosis and mitral regurgitation by their length and radiation, venous hums from patent ductus arteriosus by maneuvers designed to obliterate the hum, and supraclavicular arterial murmurs from carotid artery bruit, aortic stenosis and coarctation by similar maneuvers and blood pressure recordings. The article outlines the points of differentiation in order to arrive at a firm diagnosis and obviate concern and unnecessary referrals.
Related Concept Videos
Cardiovascular System Abnormal Findings II: Auscultation
Abnormal Heart Sounds
Gallops:
Heart Sounds
Auscultation is the process of listening to these internal body sounds using a stethoscope. The heart produces four types of sounds, but only two—S1 and S2—can usually be heard with a stethoscope.
S1, also known as the "lub" sound, is caused by the closure of atrioventricular (A-V) valves at the...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Stenosis II: Clinical features and Diagnostic Tests
Assessment of the Cardiovascular System IV: Auscultation
Normal Heart Sounds
S1 (First Heart Sound)-
S1 is made by the closure of the mitral and tricuspid valves (atrioventricular valves), marking the beginning of systole.
S2 (Second Heart Sound)-
S2 is made by the closure of the aortic and pulmonic valves (semilunar valves), marking the end of the systole.