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Updated: Jun 4, 2026

An Intact Pericardium Ischemic Rodent Model
Published on: September 2, 2021
Abstract:
The autopsy frequency of pericarditis is two to six percent excluding uremic pericarditis and pericarditis secondary to myocardial infarction. The hospital incidence in adults is about one per 1000 admissions.(7,8)Pericarditis is easily overlooked as a cause of chest pain, particularly if the pain is atypical and not too bothersome to the patient. Consideration of pericarditis in the differential diagnosis of chest pain, careful auscultation for a pericardial friction rub and the use of ultrasound to confirm pericardial effusion will increase the frequency of diagnosis. While the prognosis in viral pericarditis is usually excellent, caution is indicated in advice and follow up because of the frequency of recurrences, the possibility of irreversible myocardial damage and the occasional development of constriction. Etiologic factors other than acute viral infection must always be considered.
Insights
Pericarditis, inflammation of the heart
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Pericarditis is often overlooked in chest pain diagnosis.
- Autopsy and hospital incidence rates highlight its prevalence.
Purpose of the Study:
- To emphasize the importance of considering pericarditis in chest pain differentials.
- To improve diagnostic frequency through specific clinical approaches.
Main Methods:
- Clinical evaluation including auscultation for pericardial friction rub.
- Diagnostic confirmation using ultrasound for pericardial effusion.
Main Results:
- Early diagnosis of pericarditis can be improved with targeted assessment.
- Viral pericarditis generally has a good prognosis, but recurrences and complications can occur.
Conclusions:
- Consider pericarditis in chest pain evaluations, especially with atypical symptoms.
- Etiology beyond viral infection requires investigation.
- Monitor for recurrences and potential myocardial damage.
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