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Updated: Jun 4, 2026

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
Published on: June 7, 2015
How to manage no reflow phenomenon with local drug delivery via a rapid exchange catheter
William Wilson1, David Eccleston
1Department of Cardiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia. wmclwilson@hotmail.com
Abstract:
We describe two cases of no reflow phenomenon in the setting of primary PCI for ST elevation myocardial infarction successfully managed with intracoronary vasodilator therapy via a Clearway™ balloon catheter, where vasodilator therapy via the guiding catheter had been ineffective. Traditionally, if not given via the guiding catheter, vasodilators have been administered via an over-the-wire balloon catheter, which can be cumbersome and time consuming. The Clearway catheter is a rapid exchange balloon catheter affording rapid delivery of vasodilators to the distal infarct related artery without risk of loss of wire position. © 2010 Wiley-Liss, Inc.
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