Related Experiment Video
Updated: Jun 4, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Ventricular septal defect closure in a small children with the Amplatzer Duct Occluder II
Mohammad El Tahlawi1, Issam Kammache, Alain Fraisse
1Cardiologie Pédiatrique, Hôpital de la Timone-Enfants, 13385 Marseille Cedex 05, France.
Insights
Transcatheter closure of muscular ventricular septal defects is difficult in infants. This study shows successful closure of multiple defects using Amplatzer devices in a complex pediatric case.
Area of Science:
- Interventional Cardiology
- Pediatric Cardiac Surgery
Background:
- Transcatheter closure of muscular ventricular septal defects (mVSDs) presents unique challenges, especially in neonates and infants.
- Minimally invasive techniques are sought to improve outcomes for complex congenital heart defects.
Observation:
- A case report details the transcatheter closure of multiple apical ventricular septal defects in an infant with D-transposition of the great arteries.
- The patient had previously undergone pulmonary artery banding.
Findings:
- Two Amplatzer Duct Occluder II devices and one Amplatzer Muscular Ventricular Septal Defect Occluder were successfully deployed to close the multiple mVSDs.
- Closure was achieved during two interventional catheterization procedures.
Implications:
- The low-profile Amplatzer Duct Occluder II demonstrates feasibility for complex pediatric mVSD closure.
- Successful transcatheter device closure can be a viable option prior to surgical repair in select infant cases.
Abstract:
Transcatheter technique for muscular ventricular septal defect closure remains challenging, particularly in small patients. We report the successful use of the low profile Amplatzer Duct Occluder II for multiple ventricular septal defect closure in an infant with D-transposition of the great arteries, status postpulmonary artery banding. The multiple apical ventricular septal defects were successfully closed with two Amplatzer Duct Occluder II and one Amplatzer Muscular Ventricular Septal Defect Occluder during two interventional catheterizations. The patient subsequently underwent successful surgical repair.

