Related Experiment Video
Updated: Jun 4, 2026

Protocol to Create Chronic Wounds in Diabetic Mice
Published on: September 25, 2019
[The structure of microflora in ulcerative-necrotic lesions in patients with diabetic foot syndrome]
Abstract:
The results of dynamic microbiological investigation, conducted in 37 patients, suffering diabetic foot syndrome (DFS) during 2008-2009 yrs period, were presented. There were 103 investigations made and 169 species of microorganisms revealed. The microflora structure of surgical infection in patients with DFS was presented by S. aureus (42.85%), P. aeruginosa (32.09%), E. coli (7.66%), S. pyogenes (7.16%), Enterobacteriaceae aerogenes (6.3%), E fecales (1.97%), E. cloacae (1.97%). S. aureus have shown resistance towards ceftriaxone (66.7%), lincomycine (75%), cyprofloxacine (58.3%); P. aeruginosa--towards cephoperazone (100%), amicacine (66.6%), vancomycine (89.9%), cyprofloxacine (87.8%), imipenem (87.8%). Enterobacteriaceae are resistant towards cefuroxym (60%) and amicacine (80%).
Related Concept Videos
Diabetic Foot Ulcer
Diabetic Neuropathy
The Skin Microbiota
Diabetic Retinopathy
Peptic Ulcer Disease II: Pathophysiology
Peptic Ulcer Disease II: Pathophysiology
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.