Related Experiment Videos
[Gene cloning of human dopaminergic D3 receptor and identification of its chromosome]
B Giros1, M P Martres, P Sokoloff
1Unité de Neurobiologie et Pharmacologie (U.n. 109) de l'I.N.S.E.R.M., Centre Paul-Broca, Paris.
Abstract:
The coding region of the human dopaminergic D3 receptor gene was cloned and sequenced. The deduced amino acid sequence displays a global homology of 78% with rat D3 receptor with a deletion of 46 residues within the third intracytoplasmic loop. Southern analysis assigned the human gene to chromosome 3.