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Acne Infection01:27

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Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
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Related Experiment Video

Updated: Jun 4, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

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Published on: September 26, 2019

Atopic dermatitis in adults.

Licia Zeppa1, Veronica Bellini, Paolo Lisi

  • 1Clinical, Allergological and Venereological Dermatology Unit, Department of Medical and Surgical Specialities and Public Health, University of Perugia, Perugia, Italy.

Dermatitis : Contact, Atopic, Occupational, Drug
|February 5, 2011
PubMed
Summary

This study reveals adult atopic dermatitis (AD) is more common in women, often starting in the third decade. Key findings include typical lesion locations and the significant impact of positive patch-test reactions.

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Published on: September 27, 2017

Area of Science:

  • Dermatology
  • Epidemiology

Background:

  • Atopic dermatitis (AD) is a chronic skin condition, typically diagnosed in childhood.
  • Diagnosing adult AD can be challenging due to atypical presentations and limited lesion extension.

Purpose of the Study:

  • To investigate the epidemiological and clinical characteristics of adult atopic dermatitis.
  • To identify factors influencing adult AD presentation and diagnosis.

Main Methods:

  • Retrospective review of medical files for 332 adult atopic dermatitis patients.
  • Data collected included family/personal history of atopy, age at onset, lesion characteristics, IgE levels, and allergy testing (skin prick and patch tests).

Main Results:

  • Adult AD is more prevalent in females, with onset often occurring in the third decade of life.
  • The disease frequently affects limb flexures, eyelids, perioral areas, forehead, cheeks, and neck, typically presenting as mild to moderate.
  • Intrinsic AD accounted for 30.4% of cases, and 23.8% showed positive patch-test reactions to chemical allergens.

Conclusions:

  • Understanding the distinct epidemiological and clinical features of adult AD is crucial for accurate diagnosis and management.
  • Positive patch-test reactions in adult AD patients are significant and can impact career choices and hand dermatitis development.